Figure 3.

Sickle cell mice had significantly higher mean organ injury score than controls at 3 months, and S35 had significantly lower organ injury score than S20. Comparison of the overall mean organ injury score by study group and by feed type after 3 months of test feedings shows progressive injury in S20 but nearly stable injury in S35 which had significantly lower splenic and hepatic injury score compared with S20 mice. There were no significant differences in the scores for C20 and C35 (irrespective of the type of feed). There was a trend in lower kidney injury score among S35 compared with S20