. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Mol Imaging Biol. 2014 Dec;16(6):821–829. doi: 10.1007/s11307-014-0745-0

Table 3. Relationship between motor function (time on rotarod) and microglial activation ([¹⁸F]PBR06 uptake) and microglial proteins (TSPO, CD68, and CD11B expression) in mice following stroke induction significance (p<0.05).

Regression	Relationship	Significance (P=0.05)
[¹⁸F]PBR06 uptake on time on rotarod	Y=−0.008211×X+2.043	0.0271
TSPO expression on time on rotarod	Y=4.597×X+2.316	<0.0001
CD68 expression on time on rotarod	Y=5.702×X+65.51	<0.0001
CD11B expression on time on rotarod	Y=1.475×X+15.77	0.0029
[¹⁸F]PBR06 uptake on TSPO expression	Y=−117.3×X+403.9	0.0410
[¹⁸F]PBR06 uptake on CD68 expression	Y=-134.5×X+535.1	0.0424
[¹⁸F]PBR06 uptake on CD11B expression	Y=−45.33×X+155.4	0.0376
TSPO expression on CD68 expression	Y=0.9293×X+121.9	<0.0001
TSPO expression on CD11B expression	Y=0.3573×X+11.49	0.0002
CD68 expression on CD11B expression	Y=0.2150×X+13.27	0.0025

Table 3. Relationship between motor function (time on rotarod) and microglial activation ([18F]PBR06 uptake) and microglial proteins (TSPO, CD68, and CD11B expression) in mice following stroke induction significance (p<0.05).