Table 1.
Sequence Variants Utilized to Detect CYP2D6 alleles.
| CYP2D6 Alleles | Variant† |
|---|---|
| *2 | 2850 C>T |
| *3 | 2549 del A |
| *4 | 100 C>T, 1846 G>A, (exon 9 converstion with CYP2D7 for CYP2D6 *4N) |
| *6 | 1707 del T |
| *7 | 2935 A>C |
| *8 | 1758 G>T, 2850 C>T |
| *9 | 2615_2617delAAG |
| *10 | 100 C>T |
| *11 | 883 G>C, 2850 C>T |
| *12 | 124 G>A, 2850 C>T |
| *15 | 137_138insT |
| *17 | 1023 C>T, 2850 C>T |
| *18 | 4125_4133dupGTGCCCACT |
| *19 | 2539_2542 delAACT, 2850 C>T |
| *20 | 1973_1974 insG, 2850 C>T |
| *21 | 2573_2574 insC, 2850 C>T |
| *29 | 1659 G>A, 3183 G>A, 2850 C>T |
| *35 | 31 G>A, 2850 C>T |
| *36 | 100 C>T, exon 9 conversion with CYP2D7 |
| *38 | 2587_2590 del GACT |
| *40 | 1023 C>T, 1863_1864 ins(TTTCGCCCC)2, 2850 C>T |
| *41 | 2850 C>T, 2988 G>A |
| *42 | 2850 C>T, 3259_3260 insGT |
| *43 | 77 G>A |
| *44 | 2950 G>C |
| *45 | 1716 G>A, 2850 C>T |
| *46 | 77 G>A, 1716 G>A, 2850 C>T |
| *56 | 2850 C>T, 3201 C>T |
| *59 | 2291 G>A, 2850 C>T |
†
Defining variant in bold; additional sequence variations may be present (for details, please refer to CYP2D6 nomenclature website).