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The unbound partition coefficient (K p,uu ) of cefadroxil in rat brain ECF (A, B) and CSF (C, D) for each of the six animals. CEF represents the study in which cefadroxil is given alone (Day 1) and CEF + PRO is when cefadroxil is given in the presence of probenecid (Day 2). See Table 1 for statistical analyses.
