Table 1.
Description of 52 patients and 84 isolates associated with the Acinetobacter baumannii pulsotype 27 outbreak in Birmingham, England, 2011 to 2013
Patient no. or environmental source | Length of hospital stay (days) | Isolate no. | Time of isolation (days) | Genotype |
SNVs/plasmid loss
(p indicates loss of plasmid) |
|
---|---|---|---|---|---|---|
From admission | From start of outbreak | |||||
1 | 231 | 1a | 3 | 3 | 1.0 | 0 |
1b | 21 | 21 | 1.1 | 1,p | ||
2 | 24 | 2 | 7 | 12 | 1.0 | 0 |
4 | 88 | 4 | 25 | 36 | 2.1 | 2,4,p |
6 | 29 | 6 | 6 | 42 | 2.0 | 2 |
7 | 422 | 7 | 3 | 55 | 1.2 | 3 |
8 | 23 | 8 | 9 | 56 | 2.0 | 2 |
9 | 83 | 9 | 52 | 60 | 2.2 | 2,7 |
10 | 15 | 10 | 65 | 65 | 2.3 | 2,7,10,11 |
11 | 99 | 11 | 11 | 65 | 2.0 | 2 |
12 | 39 | 12 | 6 | 73 | 2.0 | 2 |
13 | 62 | 13 | 3 | 81 | 1.0 | 0 |
14 | 77 | 14 | 24 | 87 | 3.0 | 2,6 |
15 | LOST: not included in transmission analysis | |||||
16 | 31 | 16 | 12 | 90 | 1.0 | 0 |
17 | 535 | 17 | 24 | 94 | 2.0 | 2 |
18 | 15 | 18 | 2 | 97 | 3.0 | 2,6 |
19 | 58 | 19 | 19 | 123 | 3.0 | 2,6 |
20 | 49 | 20a | 12 | 135 | 4.0 | 2,5,9 |
20b | 13 | 136 | 4.0 | 2,5,9 | ||
21 | 19 | 21 | 1 | 138 | 4.0 | 2,5,9 |
22 | 84 | 22 | 31 | 144 | 2.4 | 2,5 |
23 | 45 | 23 | 10 | 147 | 2.5 | 2,5,8 |
24 | 218 | 24a | 25 | 165 | 4.0 | 2,5,9 |
24b | 194 | 334 | 4.10 | 2,5,9,12,p | ||
25 | 19 | 25 | 8 | 180 | 5.0 | 2,5,9,p |
26 | 197 | 26a | 17 | 180 | 4.1 | 2,5,9,13 |
26b | 25 | 188 | 4.0 | 2,5,9 | ||
26c | 100 | 263 | 4.2 | 2,5,9,13,22,p | ||
26d | 100 | 263 | 4.2 | 2,5,9,13,22,p | ||
26e | 102 | 265 | 4.6 | 2,5,9,14 | ||
26f | 102 | 265 | 4.2 | 2,5,9,13,22,p | ||
27 | 82 | 27a | 13 | 209 | 4.0 | 2,5,9 |
27b | 19 | 215 | 4.3 | 2,5,9,15 | ||
27c | 21 | 217 | 4.0 | 2,5,9 | ||
28 | 114 | 28a | 31 | 227 | LOST: mixed culture | |
28b | 43 | 239 | ||||
28c | 61 | 257 | ||||
29 | 64 | 29* | 83 | 227 (GP) | 5.0 | 2,5,9,p |
30 | 23 | 30a | 10 | 237 | 4.0 | 2,5,9 |
30b | 13 | 240 | 4.0 | 2,5,9 | ||
31 | 66 | 31a | 37 | 235 | 4.0 | 2,5,9 |
31b | 37 | 235 | MIXED | |||
31c | 39 | 237 | 4.4 | 2,5,9,18 | ||
31d | 39 | 237 | LOST: mixed culture | |||
31e | 39 | 237 | Escherichia coli | |||
31f | 39 | 237 | LOST: mixed culture | |||
31g | 39 | 237 | LOST: mixed culture | |||
31h | 39 | 237 | LOST: mixed culture | |||
31i | 46 | 244 | 4.5 | 2,5,9,17 | ||
31j | 58 | 256 | 4.0 | 2,5,9 | ||
31k | 64 | 297 | Pseudomonas aeruginosa | |||
32 | 16 | 32 | 4 | 240 | 5.0 | 2,5,9,p |
34 | 107 | 34a | 14 | 284 | 4.7 | 2,5,9,19 |
34b | 15 | 285 | 4.0 | 2,5,9 | ||
34c | 15 | 285 | 4.0 | 2,5,9 | ||
34d | 15 | 285 | 4.0 | 2,5,9 | ||
34e | 26 | 296 | 4.8 | 2,5,9,20 | ||
34f | 27 | 297 | 4.9 | 2,5,9,28 | ||
38 | 96 | 38 | 39 | 298 | LOST | |
39 | 9 | 39 | 4 | 308 | 6.1 | 2,5,9,16,23 |
40 | 53 | 40a | 11 | 334 | 6.0 | 2,5,9,16 |
40b | 13 | 336 | 6.0 | 2,5,9,16 | ||
43 | 60 | 43 | 29 | 383 | 6.0 | 2,5,9,16 |
44 | 15 | 44a | 8 | 390 | 6.0 | 2,5,9,16 |
44b | 9 | 391 | 6.0 | 2,5,9,16 | ||
44c | 11 | 391 | 6.2 | 2,5,9,16,24 | ||
44e | 11 | 393 | 6.0 | 2,5,9,16 | ||
44f | 11 | 393 | 6.0 | 2,5,9,16 | ||
Ward 1 post-patient 44 | E1 | 397 | 6.0 | 2,5,9,16 | ||
49 | 49 | 49a | 21 | 406 | 6.0 | 2,5,9,16 |
49b | 33 | 418 | 5.0 | 2,5,9,p | ||
50 | 50 | 50 | 14 | 437 | 6.0 | 2,5,9,16 |
51 | 96 | 51 | 14 | 440 | 6.0 | 2,5,9,16 |
52 | 24 | 52 | 13 | 495 | 6.0 | 2,5,9,16 |
53 | 26 | 53 | 6 | 506 | 4.11 | 2,5,9,21,p |
54 | 37 | 54 | 30 | 507 | 6.0 | 2,5,9,16 |
55 | 47 | 55 | 25 | 510 | 6.0 | 2,5,9,16 |
Burns Unit shower head post-patient 55 | E2 | 532 | 5.0 | 2,5,9,p | ||
Burns Unit shower chair post-patient 55 | E3 | 532 | 5.0 | 2,5,9,p | ||
Burns Unit patient chair post-patient 55 | E4 | 532 | 5.0 | 2,5,9,p | ||
57 | 12 | 57 | 5 | 533 | 6.0 | 2,5,9,16 |
Touch screen burns theatre post-patient 57 | E5 | 538 | 7.0 | 2,5,9,16,26,29 | ||
Anaesthetic machine burns theatre post-patient 57 | E6 | 538 | 7.0 | 2,5,9,16,26,29 | ||
Pat Slide burns theatre post-patient 57 | E7 | 538 | 6.4 | 2,5,9,16,26 | ||
Stool burns theatre post-patient 57 | E8 | 538 | 6.4 | 2,5,9,16,26 | ||
Scissors burns theatre post-patient 57 | E9 | 538 | 6.5 | 2,5,9,16,27 | ||
ECG leads burns theatre post-patient 57 | E10 | 538 | 7.0 | 2,5,9,16,26,29 | ||
58 | 72 | 58 | 6 | 535 | 6.3 | 2,5,9,16,25 |
59 | 29 | 59 | 9 | 538 | 7.1 | 2,5,9,16,26,29,30,p |
60 | 36 | 60 | 19 | 538 | 5.0 | 2,5,9,p |
61 | 15 | 61 | 9 | 542 | 7.0 | 2,5,9,16,26,29 |
62 | 27 | 62 | 4 | 543 | 7.0 | 2,5,9,16,26,29 |
63 | 29 | 63 | 15 | 544 | 7.2 | 2,5,9,16,26,29,31 |
64 | 8 | 64 | 4 | 554 | 6.0 | 2,5,9,16 |
65 | 15 | 65 | 2 | 556 | 6.0 | 2,5,9,16 |
Patients were assigned to the outbreak if an initial isolate was shown by PFGE to belong to pulsotype 27. For three patients (15, 28, 38), no MDR-Aci isolates were available for genome sequencing.
*Isolate 29 was obtained after discharge from hospital from a sample provided by a general practitioner (GP).