Table 5.

Cognitive functional scores of patients and controls (mean ± SD)

	Patients			Controls
	W1	W4	W12
MMSE	26.8 ± 1.6	25.4 ± 2.3	25.0 ± 1.7	29.3 ± 1.5
Trail making B-A test	160.3 ± 54.7ab	181.8 ± 52.1b	224.1 ± 55.1b	77.2 ± 33.3
Verbal fluency assessment	40.8 ± 10.3a	33.9 ± 11.0b	26.9 ± 11.0b	42.4 ± 8.1
Digit span backwards test	7.3 ± 1.5a	6.3 ± 1.4	5.7 ± 1.3b	7.0 ± 1.7
Digit symbol test	32.6 ± 6.5ab	26.6 ± 6.5b	22.3 ± 4.9b	45.6 ± 9.2

Abbreviations: MMSE, Mini-Mental State Examination; W1, within the first week; W4, the fourth week; W12, the 12th week.

^aP < 0.05, LSD test, comparison between W1 and W12 in patients; ^bP < 0.05, Student’s t-test, comparison between the control and patient groups.