Table 2.
Abrogation of G2/M checkpoint by YM155 in ESCC cells
| |
Eca109 |
TE13 |
||||
|---|---|---|---|---|---|---|
| Treatment | G 1 (%) | S (%) | G 2 /M (%) | G 1 (%) | S (%) | G 2 /M (%) |
|
Control |
42.7 |
26.3 |
28.0 |
45.7 |
27.4 |
23.9 |
|
YM155 |
51.4 |
22.2 |
22.6 |
59.6 |
35 |
7.8 |
|
IR |
13.6 |
23.1 |
62.5 |
23.4 |
8.7 |
66.8 |
|
IR + YM155 |
45.8 |
14.3 |
34.7 |
46.6 |
13.2 |
36.4 |
|
Treatment |
G
1
(%) |
S (%) |
G
2
/M (%) |
G
1
(%) |
S (%) |
G
2
/M (%) |
|
Control |
42.1 |
43.3 |
13.9 |
39.7 |
39.9 |
18.7 |
|
IR |
12.4 |
25.1 |
60.0 |
32.9 |
21.4 |
46.0 |
|
IR + Noc |
2.6 |
10.8 |
84.5 |
5.4 |
18.8 |
73.0 |
|
IR + YM155 |
36.8 |
31.2 |
28.9 |
43.5 |
18.2 |
35.9 |
| IR + YM155 + Noc | 20.7 | 36.0 | 41.4 | 32.1 | 11.2 | 55.9 |