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. 2014 May 4;34(12):1683–1689. doi: 10.1007/s00296-014-3029-8

Table 1.

Classification of severity, number of drugs acting over nervous system consumed by the patients and ICAF total score

No. of drugsa No. of patients (%) ICAF total score
Mean (SD)
No. of patients (%) in the category ICAF total score
Mean (SD) in the category
Mild 0 61 (26.3) 47.23 (7.86) 61 (26.3) 47.23 (7.86)
Moderate 1 73 (31.5) 48.97 (8.94) 124 (53.5) 50.15 (8.81)
2 51 (22.0) 51.84 (8.42)
Severe 3 29 (12.5) 56.62 (9.95) 47 (20.2) 57.52 (10.53)
4 14 (6.0) 58.70 (12.98)
5 4 (1.7) 59.97 (4.59)
Total 232 (100) 232 (100)

aIncludes antidepressants, benzodiazepines, hypnotics, anticonvulsants, antipsychotic and antihistaminic, with the exclusion of analgesics (any type) and NSAID