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. 2014 Aug 27;7:56. doi: 10.1186/s13041-014-0056-z

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Copyright © 2014 François et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Ultrastructure of cortex after acute LPS-induced inflammation. TEM cortical images of 0.9% NaCl-injected mice (A and B) and 10 mg/kg LPS-treated mice (2 injections per 24 h, images C and D). No alteration of tissue integrity was observed in low magnification images (A and C), myelin rounded axons marked with white arrow. Images B and D represent magnified region of interest of the white square in A and C, respectively. In these magnified images, mitochondria appeared with intact cristae (mt), endoplasmic reticulum (ER) was present with ribosomes and lysosomes (L) were observed. Five sections in each area (cortex and hippocampus) were observed for each mouse brain.