Table 3.
Regression coefficients for changes in metabolic variables with changes in weight and AT depots
Glucose (mg/dL) | HbA1c % (mmol/mol) | Cholesterol (mg/dL) | HDL-C (mg/dL) | Cholesterol/HDL | Triglycerides (mg/dL) | Systolic BP (mmHg) | Diastolic BP (mmHg) | |
---|---|---|---|---|---|---|---|---|
Weight (kg) | ILI 2.1† | ILI 0.04 (0.4)‡ | M 1.7† | −0.35* | ILI 0.07‡ | 2.2† | ILI 0.65* | ILI 0.60‡ |
TAT (kg) | ILI 2.0† | ILI 0.03 (0.3)* | M 1.8† | F −0.56† | ILI 0.07‡ | 2.1† | 0.59* | ILI 0.58‡ |
SAT | ILI 2.5† | ILI 0.04 (0.4)* | M 2.7† | F −0.75† | ILI 0.09‡ | 2.5* | 0.85* | ILI 0.82‡ |
Arm | ILI 0.51* | 26.6† | ILI 6.1‡ | |||||
Trunk | ILI 4.2† | ILI 0.06 (0.7)* | ILI 3.1† | F −1.18† | ILI 0.12‡ | 3.8* | 1.5† | ILI 1.2‡ |
Leg | ILI 7.0* | ILI 0.15 (1.6)* | ILI 7.5† | F −1.40* | ILI 0.30‡ | ILI 2.5‡ | ||
VAT | ILI 8.8† | ILI 0.13 (1.4)* | ILI 5.6* | −1.60* | 0.26‡ | 12.2‡ | 2.9* | 2.2‡ |
IMAT | ILI 17.7* | 0.27* | M 25.3† | |||||
Arm | M 3.8* | |||||||
Trunk | ILI 41.5* | M 0.75* | M 41.7* | |||||
Leg | 17.2* | F 7.1* |
The regression coefficient estimates the change in the metabolic variable associated with a 1-kg change in the AT compartment. Changes in compartments and metabolic variables were expressed as differences, year 1 minus baseline. When associations were different by group or sex, the qualifier is shown. F, females; M, males.
*P < 0.05.
†P < 0.01.
‡P < 0.001.