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. 2014 Nov 13;63(12):4045–4056. doi: 10.2337/db14-0466

Figure 1.

Figure 1

Dgcr8 KO mice showed increased but pale BAT. A: PCR genotyping results in interscapular BAT (BAT), Sub WAT (SUB), and Epi WAT (EPI) from 12-week-old control (CON) and KO mice (upper panel) or in mature adipocytes and SVF from each fat tissue (lower panel). B: Body weights curves of CON and KO mice at indicated times under normal chow diet (n = 8 each group). C: Food intake of CON and KO mice at 16 weeks old. D: Photographs of BAT, SUB, and EPI from 16-week-old CON and KO mice. E: Weight of each fat tissue in CON and KO mice (n = 8 each group). F: Representative data of hematoxylin and eosin staining of fat tissues from 16-week-old CON and KO mice. Scale bar: 50 µm. The relative cell number in each tissue was estimated by the ratio between tissue weight and cell volume and then normalized to the cell number in CON tissue for presentation on the right. G: Fat mass (left panel) and lean mass (right panel) from 14-week-old CON and KO mice. Blood glucose levels during GTT (H) and ITT (I) of 14-week-old mice (n = 8 each group). J: Plasma insulin levels of 16-week-old mice (n = 8 each group). *P < 0.05, Student t test. Data are shown as means ± SEM.