Table 6.
Analyses Testing the Effects of Covarying Out rs4973397 on Imputed SNPs in Same Region on Chromosome 2 with p Values Less than 10−7 in GWAS
| SNP | Chr | Position | Original p value | Adjusted p value |
|---|---|---|---|---|
| \rs12694890 | 2 | 232276553 | 8.21E-08 | 0.40291 |
| rs12998237 | 2 | 232276651 | 8.20E-08 | 0.40255 |
| rs12999051 | 2 | 232276992 | 7.86E-08 | 0.39270 |
| rs12993290 | 2 | 232279687 | 6.15E-08 | 0.45461 |
| rs4973392 | 2 | 232286552 | 6.10E-08 | - |
| rs12622248 | 2 | 232289127 | 7.80E-08 | 0.74416 |
| rs6721978 | 2 | 232290157 | 9.75E-08 | 0.88992 |
| rs12614599 | 2 | 232290640 | 3.96E-08 | 0.31522 |
| rs12614600 | 2 | 232290672 | 6.99E-08 | 0.87376 |
| rs4973396 | 2 | 232291320 | 5.47E-08 | 0.32961 |
| rs4973397 | 2 | 232291471 | 5.49E-08 | 0.22324 |
| rs16825944 | 2 | 232291866 | 9.96E-08 | 0.91805 |
| rs1868457 | 2 | 232296082 | 3.28E-09 | 0.01189 |
Chr = Chromosome; SNP = single nucleotide polymorphism; Position = base pair position in build GRCh37 (hg19); Original p value = p value from GWAS of imputed SNP data; Adjusted p value = p value after covarying out rs4973397 of imputed SNPs.