Table 1.
Baseline demographic and clinical characteristics
| Major ischaemic stroke (N=523) | Intracerebral haemorrhage (N=113) | p value | ||
|---|---|---|---|---|
| Mean age, years (SD) | 78·7 (11·0) | 75·9 (12·7) | 0·02 | |
| Men | 228 (44%) | 60 (53%) | 0·08 | |
| Diabetes | 76 (15%) | 11 (10%) | 0·23 | |
| Smoking | 0·95 | |||
| Never | 269 (51%) | 57 (50%) | .. | |
| Ex-smoker | 205 (39%) | 46 (41%) | .. | |
| Current smoker | 49 (9%) | 10 (9%) | .. | |
| Previous hypertension | 352 (67%) | 67 (59%) | 0·13 | |
| Previous atrial fibrillation | 169 (32%) | 23 (20%) | 0·01 | |
| Previous myocardial infarction | 84 (16%) | 6 (5%) | 0·002 | |
| Previous angina | 107 (20%) | 12 (11%) | 0·016 | |
| Previous transient ischaemic attack | 75 (14%) | 16 (14%) | 1·00 | |
| Previous stroke | 98 (19%) | 11 (10%) | 0·02 | |
| Previous peripheral vascular disease | 58 (11%) | 7 (6%) | 0·17 | |
| Medication | ||||
| Prior antihypertensives | 352 (67%) | 54 (48%) | 0·0001 | |
| Prior statin | 144 (28%) | 23 (20%) | 0·13 | |
| Prior antiplatelet therapy | 258 (49%) | 33 (29%) | 0·0001 | |
| Number of premorbid BP readings | ||||
| Mean (SD) | 21·2 (16·7) | 19·2 (15·0) | 0·26 | |
| Median (IQR) | 17 (8–31) | 16 (7–32) | 0·32 | |
| Stroke cause (TOAST subtype) | ||||
| Large artery disease | 37 (7%) | .. | .. | |
| Cardioembolic | 211 (40%) | .. | .. | |
| Small artery disease | 48 (9%) | .. | .. | |
| Other determined cause | 15 (3%) | .. | .. | |
| Undetermined cause | 77 (15%) | .. | .. | |
| Unknown cause | 120 (23%) | .. | .. | |
| More than one cause | 15 (3%) | .. | .. | |
| Location of intracerebral haemorrhage | ||||
| Lobar | .. | 45 (40%) | .. | |
| Deep or posterior | .. | 66 (58%) | .. | |
| Both lobar and deep | .. | 1 (1%) | .. | |
| Unknown | .. | 1 (1%) | .. | |
Data are n (%) unless otherwise specified. BP=blood pressure. TOAST=Trial of Org 10172 in Acute Stroke Treatment.