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. 2014 Oct 1;9(19):1731–1739. doi: 10.4103/1673-5374.143415

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ki-67 immunohistochemistry in the dentate gyrus of the control and SCO-treated (1–4 weeks) groups.

Ki-67-immunoreactive cells (arrows) in the 4 weeks-SCO-treated group (E) are much less than those in the control group (A). (B–D) 1–3 weeks-SCO-treated groups. Scale bar: 50 μm. (F) Mean number of Ki-67-immunoreactive cells per section in the dentate gyrus. Data were analyzed using one-way analysis of variance followed by a Tukey's multiple range method (n = 7 per group; *P < 0.05, vs. the control group; #P < 0.05, vs. the former time point group). The bars indicate the mean ± SEM. SCO: Scopolamine; ML: molecular layer; GCL: granule cell layer; SGZ: subgranular zone; PL: polymorphic layer; I: control; II: SCO 1 week; III: SCO 2 weeks; IV: SCO 3 weeks; V: SCO 4 weeks.