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. 2014 Oct 1;9(19):1731–1739. doi: 10.4103/1673-5374.143415

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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BrdU immunohistochemistry in the dentate gyrus of the control and 4 weeks-SCO-treated groups.

The number of BrdU-positive cells (arrows) in the SGZ (indicated by dashed wavy lines) of the 4 weeks-SCO-treated group (B, b) is significantly decreased compared with that in the control group (A, a). Scale bars: 200 μm for A, B, and 50 μm for a and b. (C) The mean number of BrdU-positive cells per section in the dentate gyrus. Data were analyzed using an independent samples t-test (n = 7 per group; *P < 0.05, vs. the control group). The bars indicate the mean ± SEM. BrdU: 5-Bromo-2′-deoxyuridine; SCO: scopolamine; ML: molecular layer; GCL: granule cell layer; SGZ: subgranular zone; PL: polymorphic layer.