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. 2014 Oct 1;9(19):1753–1762. doi: 10.4103/1673-5374.143419

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pathological changes in the cerebral infarction area in rats with cerebral ischemia-reperfusion injury (hematoxylin-eosin staining, light microscopy, × 400).

(A) Sham surgery group. Neural cells are normal looking. (B, C) 0 and 2 hours after middle cerebral artery occlusion, neural cells display no obvi-ous change. (D) 6 hours after middle cerebral artery occlusion, neural cells appeared slightly swollen (arrows). (E) 12 hours after middle cerebral artery occlusion, neural cells appeared swollen, with a bigger volume and nuclear condensation (arrows). (F) 24 hours after middle cerebral artery occlusion, no complete cell membranes are detectable (arrow).