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. 2014 Oct 1;9(19):1753–1762. doi: 10.4103/1673-5374.143419

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ultrastructural alterations in the cerebral infarction area in rats with cerebral ischemia-reperfusion injury (electron microscope).

(A) Normal-looking neural cells in the sham surgery group (× 8,000). (B, C) Early apoptosis (arrows) 4 hours after middle cerebral artery occlu-sion (× 8,000). (D) Mitochondrial (arrows) changes 24 hours after middle cerebral artery occlusion (× 15,000). (E) Intermediate stages of apopto-sis (arrow) 2 days after middle cerebral artery occlusion (× 8,000). (F) Pyknosis (arrow) 4 days after middle cerebral artery occlusion (× 8,000). (G) Late stage of apoptosis (arrows) 6 days after middle cerebral artery occlusion (× 15,000). (H) Partial mitochondrial (arrows) recovery 18 days after middle cerebral artery occlusion (× 15,000).