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. 2014 Oct 1;9(19):1753–1762. doi: 10.4103/1673-5374.143419

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Alterations in the permeability of the blood-brain barrier in rats after middle cerebral artery occlusion.

(A) Sham-surgery group; (B) Evans blue (EB) accumulation 2 hours after middle cerebral artery occlusion (arrow); (C) EB accumulation (arrow) 24 hours after middle cerebral artery occlusion; (D) 10 days after middle cerebral artery occlusion; (E) EB content at different time points. Data are expressed as the mean ± SD. One-way analysis of variance was used to evaluate differences between groups. Paired t-test was applied for intergroup comparisons. *P < 0.05, **P < 0.01, vs. sham surgery and control groups. h: Hour(s); d: day(s).