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. 2014 Jul 8;29(11):1475–1483. doi: 10.1007/s11606-014-2947-1

Table 2.

PAD and Post-PAD Mortality by Treatment Group

Chlorthalidone Amlodipine Lisinopril Amlodipine vs. chlorthalidone Lisinopril vs. chlorthalidone
Number of events 6-Year rate per 100 persons (SE) Number of events 6-Year rate per 100 persons (SE) Number of events 6-Year rate per 100 persons (SE) HR (95 % CI) P HR (95 % CI) P
PAD 402 3.2 (0.2) 198 2.7 (0.2) 230 3.4 (0.3) Univariate:
0.82 (0.70–0.98) 0.027 0.96 (0.82–1.13) 0.651
Multivariate*:
0.86 (0.72–1.03) 0.099 0.98 (0.83–1.17) 0.847
10-Year rate per 100 persons (SE) 10-Year rate per 100 persons (SE) 10-Year rate per 100 persons (SE)
Post-PAD mortality 258 74.2 (3.0) 119 74.5 (5.8) 143 73.2 (4.7) Univariate:
0.92 (0.74–1.15) 0.454 0.95 (0.77–1.18) 0.651
Multivariate*:
0.96 (0.76–1.23) 0.762 1.01 (0.80–1.27) 0.918

*Adjusted for baseline variables of age, race, ethnicity, gender, heart rate, pulse pressure, aspirin use, history of atherosclerotic cardiovascular disease, history of coronary heart disease, history of diabetes, current smoking, ever smoking, BMI, and estimated glomerular filtration rate

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