Table 4.

Changes in Psychobehavioral Responses Across Adjuvant Therapy

Variable	Possible score range	Mean score before adjuvant therapy	Mean score at 2 months	Mean score at 6 months	F-Value	p-Value
Stress (total)	0–75	30.3±14.8	22.6±15.2	19.8±15.7	12.1	<0.001
Intrusion	0–35	14.6±8.4	10.4±7.9	8.9±8.3	12.8	<0.001
Avoidance	0–40	15.6±8.3	12.1±9.0	10.9±9.3	7.4	0.001
Mood (total)	0–148	45.2±27.2	35.7±25.3	32.6±26.6	8.7	<0.001
Anxiety	0–24	8.8±5.9	4.9±4.7	4.5±5.3	24.7	<0.001
Depression	0–32	6.1±6.1	4.6±5.7	4.1±6.2	4.1	0.02
Anger	0–28	4.6±5.9	4.0±5.7	3.6±5.4	1.6	0.21
Lack of vigor	0–24	13.0±5.4	10.3±6.3	9.3±6.5	9.1	<0.001
Fatigue	0–20	7.1±5.7	7.9±6.1	7.2±6.0	.65	0.53
Confusion	0–20	5.6±4.4	4.1±3.8	3.9±4.3	7.2	0.001
Quality of life (total)		90.2±25.4	82.1±29.9	77.1±40.4	7.7	0.001
Physical	0–28	15.2±9.7	14.6±8.9	13.2±10.2	3.3	0.04
Emotional	0–24	13.4±6.2	13.4±6.2	11.9±8.5	4.9	0.009
Functional	0–28	18.8±6.4	16.4±8.5	16.7±9.1	4.3	0.02
Social	0–28	22.7±4.4	19.8±7.9	18.5±9.2	10.7	<0.001
Additional	0–40	20.1±7.7	18.1±8.5	16.6±9.9	8.1	0.001

Mean values are expressed with standard deviations.