FIG. 4.

The 3D contour of the activated regions in response to bilateral forepaw stimulation. The colored contours were created from the averaged 3D functional beta maps of sham (green), IO (yellow), and IO+ablation (red) rats with a threshold at 2. In the 3D contour, both primary cortical regions (FP-S1) and the S2 regions (smaller blobs) were detected. In the overlap maps, no difference was detected between sham and IO 3D contours, but there was a clear expansion in the IO+ablation group toward the barrel cortex as shown by the red arrow (details in the Supplementary Movie S1).