Table 5.

Univariate and Multivariate Single Locus Association with 6 months Glasgow Outcome Score outcome after Traumatic Brain Injury

		Univariate analysis		Multivariate analysis
		Good vs. poor outcome		Good vs. poor outcome
SNPs	Model	OR (95% CI)	p	OR (95% CI)	p
rs335929	Dom	0.60 (0.35–1.02)	0.06	0.49( 0.25–1.00)	0.051
	Rec	0.91 (0.33–2.52)	0.85	0.80 (0.21–3.16)	0.76
	Allele difference	0.71 (0.46–1.09)	0.12	0.61 (0.35–1.08)	0.09
rs3763043	Dom	2.46 (1.47–4.12)	0.0005	2.39 (1.25–4.58)	0.008
	Rec	2.91 (1.31–6.44)	0.008	5.15 (1.60–16.5)	0.006
	Allele difference	2.08 (1.42–3.04)	0.0001	2.30 (1.38–3.83)	0.001
rs11661256	Dom	1.14 (0.58–2.27)	0.68	0.24 (0.07–0.75)	0.014
	Rec	–	–	–	–
	Allele difference	1.02 (0.54–1.92)	0.93	0.24 (0.07–0.75)	0.014
rs335931	Dom	0.55 (0.32–0.95)	0.03	0.40 (0.19–0.82)	0.012
	Rec	0.58 (0.16–2.06)	0.41	0.27 (0.05–1.44)	0.126
	Allele difference	0.61 (0.39–0.97)	0.039	0.44 (0.24–0.82)	0.009
rs4800773	Dom	0.88 (0.53–1.47)	0.63	0.96 (0.48–1.89)	0.91
	Rec	1.61 (0.82–3.14)	0.16	2.18 (0.81–5.89)	0.12
	Allele difference	1.07 (0.74–1.54)	0.70	1.17 (0.72–1.92)	0.51
rs3875089	Dom	0.84 (0.43–1.65)	0.62	0.22 (0.07–0.65)	0.006
	Rec	–	–	–	–
	Allele difference	0.77 (0.42–1.41)	0.39	0.18 (0.07–0.50)	0.0009

R, odds ratio; CI, confidence interval.