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The pathological examination result of pancreatic islets in STZ-induced diabetic rats. (a) Pancreatic islet from a normal mouse. (b) Pancreatic islet from STZ-induced diabetic rats with no treatment, severe degranulation of most β-cells in this islet. (c) and (d) Pancreatic islet from STZ-induced rats treated with Met and Glic, respectively. (e) and (f) Pancreatic islet from STZ-induced rats treated with TNTL (1.26 and 0.63 g/kg b.w., resp.).
