Table 2.
Frequency Distributions for Variables used in Propensity Score Matching U.S. Department of Defense Observational Study
| Before Matching |
After PS Matching |
|||
|---|---|---|---|---|
| Variables | Varenicline N=19933 |
Nicotine Patch N = 15867 |
Varenicline N=13215 |
Nicotine Patch N=13215 |
| N (%) / Mean (SD) | N (%) / Mean (SD) | N (%) / Mean (SD) | N (%) / Mean (SD) | |
| Age | 42.1 (14.3) | 35.1 (12.6) | 36.8 (12.4) | 36.8 (12.8) |
| Charlson comorbidity score | 0.37 (0.97) | 0.21 (0.77) | 0.23 (0.76) | 0.24 (0.83) |
| Inpatient admission | 2054 (10.30) | 1756 (11.07) | 1377 (10.42) | 1408 (10.65) |
| Diagnoses in previous year | ||||
| Anxiety | 1054 (5.29) | 692 (4.36) | 594 (4.49) | 619 (4.68) |
| Chronic pain | 78 (0.39) | 36 (0.23) | 29 (0.22) | 35 (0.26) |
| Delusional disorder | 3 (0.02) | 5 (0.03) | 3 (0.02) | 4 (0.03) |
| Depressive disorder | 1097 (5.50) | 694 (4.37) | 592 (4.48) | 630 (4.77) |
| Drug-induced mental disorder | 45 (0.23) | 42 (0.26) | 31 (0.23) | 33 (0.25) |
| Episodic and mood disorder | 879 (4.41) | 595 (3.75) | 510 (3.86) | 529 (4.00) |
| Other nonorganic psychosis | 34 (0.17) | 25 (0.16) | 16 (0.12) | 20 (0.15) |
| Personality disorder | 101 (0.51) | 121 (0.76) | 76 (0.58) | 83 (0.63) |
| PTSD | 247 (1.24) | 237 (1.49) | 164 (1.24) | 173 (1.31) |
| Schizophrenia | 41 (0.21) | 30 (0.19) | 25 (0.19) | 25 (0.19) |
| Substance abuse | 280 (1.40) | 382 (2.41) | 225 (1.70) | 240 (1.82) |
| Suicide attempt | 14 (0.07) | 21 (0.13) | 13 (0.10) | 14 (0.11) |
| Transient mental disorder | 48 (0.24) | 38 (0.24) | 30 (0.23) | 32 (0.24) |
| Neuropsychiatric (all above) | 2595 (13.02) | 1762 (11.10) | 1477 (11.18) | 1539 (11.65) |
| Filled prescriptions in previous year | ||||
| Any Antipsychotic medication | 560 (2.81) | 451 (2.84) | 343 (2.60) | 371 (2.81) |
| Bupropion | 2074 (10.40) | 2301 (14.50) | 1419 (10.74) | 1507 (11.40) |
| Pain medication | 14149 (70.98) | 10905 (68.73) | 9190 (69.54) | 9170 (69.39) |
| Any Psychiatric medication | 7629 (38.27) | 5260 (35.42) | 4403 (33.32) | 4567 (34.56) |
| Sleep medication | 2263 (11.35) | 1345 (8.48) | 1174 (8.88) | 1220 (9.23) |
| Other smoking cessation medication | 424 (2.13) | 1061 (6.69) | 415 (3.14) | 434 (3.28) |
| SSRIs | 2964 (14.87) | 1759 (11.09) | 1521 (11.51) | 1593 (12.05) |
| TCAs | 849 (4.26) | 502 (3.16) | 419 (3.17) | 463 (3.50) |
| Marital status | ||||
| Married | 10746 (53.91) | 8831 (55.66) | 7586 (57.40) | 7689 (58.18) |
| Other | 9187 (46.09) | 7036 (44.34) | 5629 (43.60) | 5526 (41.82) |
| Race | ||||
| White | 10071 (50.52) | 9388 (59.17) | 7738 (58.55) | 7723 (58.44) |
| Other | 9862 (49.48) | 6479 (40.83) | 5477 (41.45) | 5492 (41.56) |
| Sex | ||||
| Female | 8763 (43.96) | 5094 (32.11) | 4814 (36.43) | 4737 (35.85) |
| Male | 11168 (56.04) | 10770 (67.89) | 8399 (63.57) | 8476 (64.15) |