Table 1.

Peak ethanol levels (mg%) and ethanol elimination rate (mg%/min) in female P rats (n = 5–7/group) following acute i.p. exposure to 1 mg/kg caffeine dissolved in 0.5 g/kg 15% w/v ethanol (low), or 30 mg/kg caffeine dissolved in 2.0 g/kg 15% w/v ethanol (high), or equivalent doses of 15% w/v ethanol alone.

Treatment Condition	Ethanol Peak Level (mg%)	Ethanol Elimination(mg%/min)
Ethanol Low	48 ± 5	−0.70 ± 0.05
Ethanol/Caffeine Low	68 ± 6	−0.92 ± 0.14
Ethanol High	235 ± 10	−0.78 ± 0.17
Ethanol/Caffeine High	222 ± 19	−0.68 ± 0.02

^*, indicates p < 0.05 vs. ethanol alone group.