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. Author manuscript; available in PMC: 2014 Nov 20.
Published in final edited form as: J Proteome Res. 2013 Jul 11;12(8):3689–3696. doi: 10.1021/pr400274w

Table 2.

Quantitative analysis of proteins from BAL and lung tissues using iTRAQ

Description 116/115 118/117 119/113
Neutrophil elastase 0.646 1.356 29.382
Integrin alpha-M 0.713 2.146 20.499
Cullin-4B 0.883 0.921 15.264
Napsin-A 0.286 4.252 5.145
LAMP2 0.479 1.772 4.675
Cathepsin D 0.436 61.061 3.897

BPI fold-containing family B member 2 0.789 1.585 3.064

Neutrophil gelatinase-associated lipocalin 0.873 0.961 2.695
Ig alpha-2 chain C region 0.665 5.955 1.799
Myeloperoxidase 0.816 0.884 1.596
Immunoglobulin J chain 0.592 10.353 1.456
Galectin-3-binding protein 0.560 8.286 0.981
Hemopexin 0.711 4.157 0.920
Alpha-1-antitrypsin 0.986 0.998 0.623
Beta-2-glycoprotein 1 0.407 11.946 0.504
Sushi domain-containing protein 2 0.030 0.256 0.487
Ceruloplasmin 0.986 0.998 0.458
Clusterin 0.639 3.438 0.419
Plasma protease C1 inhibitor 0.561 8.115 0.397
Plasma kallikrein 0.951 4.237 0.371
Complement factor B 0.400 9.984 0.297
Afamin 0.549 13.601 0.297
Complement C4-A 0.347 4.982 0.262
Kininogen-1 0.584 5.449 0.225
Ig mu chain C region 0.390 3.613 0.184
Haptoglobin 0.574 22.625 0.142
Ig gamma-2 chain C 0.671 10.092 0.104
Ig gamma-1 chain C region 0.742 5.833 0.098
Ig gamma-4 chain C region 0.649 5.405 0.084
Ig gamma-3 chain C region 0.739 4.995 0.067
Complement C3 0.989 5.559 0.060
Fibrinogen beta chain 0.302 0.998 0.036
113 Pooled benign BAL
115 Pooled non-tumor tissues from early stage tumor
116 Pooled tumor tissues from early stage tumor
117 Pooled non-tumor tissues from late stage tumor
118 Pooled tumor tissues from late stage tumor
119 Pooled cancer BAL