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. 2014 Oct 15;7(10):3430–3438.

Table 2.

Correlation between p16 immunohistochemistry and HPV in situ hybridization esophageal squamous cell carcinoma

Total p16-positive p16-negative

(N = 105) (N = 39) (N = 66)

HPV Status No. (%) No. (%) No. (%) P Value Kappa Value
Positive 29 (27.6) 25 (64.1) 4 (6.1) < 0.001 0.61
Negative 76 (72.4) 14 (35.9) 62 (93.9)

P and Kappa values were calculated with the use of Pearson’s chi-square test and Cohen Kappa test, respectively.