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. 2013 Jun 6;28(10):1443–1446. doi: 10.1002/mds.25520

Table 1.

Demographic and polysomnographic data of 33 IPD patients and 37 age-matched controls

Mean ± SD or No. (%)
Variable IPD patients Controls P
Demographic data
 Age, y 65.5 ± 11.6 66.7 ± 9.0 0.66a
 Sex: Men/women 12/21 21/16 0.09
 Educational level, y 12.2 ± 3.7 12.6 ± 3.5 0.77b
 MMSE score 28.82 ± 1.7 28.78 ± 3.0 0.95b
 BMI, kg/m2 25.3 ± 3.9 27.0 ± 4.0 0.08b
 Hoehn-Yahr stage 2.0 ± 0.5
 PD duration, y 1.9 ± 1.3
 Levodopa dosage, mg 238.3 ± 331.5
 Dopamine agonists, mgc 1.0 ± 2.0 0.06 ± 0.3 <0.01
 Antidepressants 8 (24) 6 (16) 0.40
 Sedatives 4 (12) 5 (13) 0.86
 Total sleep time, min 308.8 ± 58.0 325.8 ± 63.5 0.24b
Polysomnographic data
 Total sleep time, min 308.8 ± 58.0 325.8 ± 63.5 0.24b
 Sleep latency, min 36.7 ± 27.3 36.3 ± 26.5 0.95a
 Sleep efficiency, % 72.1 ± 15.2 74.4 ± 12.9 0.49a
 NREM sleep stage 2, min 175.2 ± 47.0 176.4 ± 51.8 0.98d
 NREM sleep stage 2, % 43.4 ± 11.4 44.5 ± 13.3 0.61b
 NREM sleep stage 3, min 51.2 ± 45.7 61.9 ± 47.14 0.34a
 NREM sleep stage 3, % 13.6 ± 12.0 14.6 ± 9.2 0.69a
 REM sleep stage, min 43.0 ± 29.6 53.7 ± 25.9 0.09d
 REM sleep stage, % 11.1 ± 7.1 13.6 ± 7.1 0.15a
 Index of apnea/hypopnea/h 2.5 ± 4.9 2.1 ± 3.3 0.71a
 Index of periodic leg movements/h 4.7 ± 14.9 5.8 ± 13.2 0.75a
 REM sleep muscle atonia, % 79.9 ± 30.9 92.7 ± 22.4 0.0497a
 Awakenings/h 6.0 ± 4.0 4.5 ± 3.2 0.10a
 Arousals/h 7.8 ± 4.8 7.9 ± 6.7 0.94a
a

Welch analysis of variance.

b

Mann-Whitney test.

c

Expressed in pergolide equivalents, with 1 mg of pergolide = 10 mg bromocriptine = 3 mg of ropinirole = 1 mg of pramipexole.

d

Analysis of variance (log values).

SD, standard deviation; IPD, idiopathic Parkinson’s disease; MMSE, Mini-Mental State Examination; BMI, body mass index; PD, Parkinson’s disease; NREM, non-rapid eye movement; REM, rapid eye movement.