Table 1.
Yeast SWI/SNF complex subunits
| Gene | Open reading frame | Description | Human homologue |
|---|---|---|---|
| ARP7* | YPR034W | Actin-related protein involved in transcriptional regulation | BAF53 |
| ARP9* | YMR033W | Actin-related protein involved in transcriptional regulation | BAF53 |
| RTT102 | YGR275W | Chromosome maintenance | |
| SNF2 | YOR290C | Transcriptional regulation | BRG1 or hBRM |
| SNF5 | YBR289W | Transcriptional regulation | hSNF5 |
| SNF6 | YHL025W | Transcriptional regulation | |
| SNF11 | YDR073W | Transcriptional regulation | |
| SWI1* | YPL016W | Regulates transcription by remodeling chromatin; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1, and SUC2 | BAF250/hOSA1 |
| SWI3 | YJL176C | Regulates transcription by remodeling chromatin; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1, and SUC2 | BAF155, BAF170 |
| SWP82 | YFL049W | Role not identified yet | |
| TAF14 | YPL129W | Involved in RNA polymerase II transcription initiation and in chromatin modification |
Notes:
*
Deletion mutant is nonviable and was not included in this study.