Table 2.

Meta-analysis for the association of UBQ-8i polymorphism with AD risk.

	No. of studies	OR (95% CI)	P value	I2 (%)	Pheterogeneity
Overall	12	1.15 (1.05–1.25)	0.002	0	0.58
Adjusted	5	1.15 (1.12–1.30)	0.02	0	0.83
APOE ɛ4 carriers	8	1.28 (1.05–1.56)	0.01	4	0.40
APOE non-ɛ4 carriers	8	1.25 (1.04–1.50)	0.02	0	0.85
EOAD	3	1.12 (0.95–1.31)	0.17	0	0.77
LOAD	7	1.17 (1.05–1.31)	0.005	15	0.32

EOAD – early-onset Alzheimer’s disease; LOAD – late-onset Alzheimer’s disease.