TABLE . Summary of disease associations, geographical distribution, ecotope and host of Trypanosoma cruzi discrete typing units TcI to TcVIa .

TcI	The main agent of Chagas disease in the northern part of Latin America and in the Amazon Region. Found widely in silvatic cycles elsewhere. Many silvatic reservoirs, especially opossums (Didelphis). Genetically highly diverse.
TcII	The principal agent of Chagas disease in Atlantic and Central Brazil. Occasionally found further North. Several silvatic reservoirs have been reported, but wild host species are not fully known.
TcIII	Rare in human infections, sporadic in dogs. Silvatic burrowing reservoirs, especially armadillos (Dasypus) in South America. Some isolates have been found virulent to mice. Genetically diverse.
TcIV	Secondary agent of Chagas disease in Venezuela. Arboreal (primates, raccoons) and terrestrial reservoirs. Silvatic, along with TcI, in North America.
TcV and TcVI	Common agents of Chagas disease in the Gran Chaco/Southern Cone region. Rarely silvatic, thus reservoirs, if any, are poorly known. Possible anthropogenic or peridomestic origins. Both genetically conserved. Recent hybrids of TcII and TcIII.

a: information compiled from Miles et al. (2009), Guhl and Ramírez (2011) and Zingales et al. (2012).