Table 3d.

Multivariate analysis of risk factors for 30- and 90-day mortality after a major hepatectomy

Variable	30-day mortality			90-day mortality
	HR	95% CI	P-value	HR	95% CI	P-value
Gender	1.88	0.78–4.52	0.158	1.08	0.52–2.24	0.849
ASA class	3.60	1.45–8.96	0.014	2.13	0.94–4.81	0.072
Pre-op albumin	0.94	0.45–1.95	0.861	0.66	0.33–1.30	0.233
Pre-op INR	1.21	0.11–6.64	0.379	1.56	0.06–7.28	0.720
Pre-op total bilirubin	1.05	0.89–1.23	0.590	1.05	0.75–1.19	0.628
Portal vein embolization	1.06	0.21–5.38	0.936	1.30	0.34–4.93	0.704
Bile duct resection	1.90	0.77–4.69	0.163	1.56	0.69–3.57	0.285
EBL	1.00	1.00–1.01	0.131	1.00	1.00–1.01	0.421
Intra-op transfusion	2.79	1.01–7.70	0.047	3.32	1.40–7.86	0.012
Cancer diagnosis	6.43	1.14–36.34	0.049	5.36	1.43–20.12	0.008
Cirrhosis	7.56	2.34–24.45	0.001	6.84	2.42–19.35	<0.001
Phos nadir after POD3	2.39	1.09–5.72	0.045	2.11	0.99–4.49	0.054

Statistically significant variables (P < 0.05) indicated in bold. ASA, American Society of Anesthesiology; CI, confidence interval; EBL, estimated blood loss; HR, hazard ratio; INR, international normalized ratio; POD3, postoperative day 3.