Table 2.

Epstein–Barr virus (EBV) epitope-specific interferon (IFN)-γ production measured by enzyme-linked immunospot (ELISPOT) assay in four X-linked inhibitor of apoptosis (XIAP)^G466X patients

	MHC class I
II-5	A 0201				A 0301	B 3501
Peptide	GLC	CLG	FLY	YVL	RLR	EPL	YPL	HPV
Protein	BMLF1	LMP2	LMP2	BRLF1	EBNA3	BZLF1	EBNA3	EBNA1
Cycle	Lytic	Latent	Latent	Lytic	Latent	Lytic	Latent	Latent
ELISPOT	25	88	88	15	63	1500	60	183
III-1	B 4501	B 4001
Peptide	AEN	IED	SEN
Protein	BRLF1	LMP2	BZLF1
Cycle	Lytic	Latent	Lytic
ELISPOT	1478	1478	133
III-2	B 4501	B 4001
Peptide	AEN	IED	SEN
Protein	BRLF1	LMP2	BZLF1
Cycle	Lytic	Latent	Lytic
ELISPOT	1498	1498	73
III-6	A 1101		B 3501
Peptide	IVT	AVF	EPL	YPL	HPV
Protein	EBNA3B	EBNA 3B	BZLF1	EBNA3	EBNA1
Cycle	Latent	Latent	Lytic	Latent	Latent
ELISPOT	228	268	1493	28	60

	MHC class II
II-5	DRB1 0101		DQB1 0501
Peptide	TSL	GPW	SDD
Protein	EBNA1	EBNA3A	EBNA3C
Cycle	Latent	Latent	Latent
ELISPOT	0	0	0
III-1	DRB1 0401			DRB1 0701	DQB1 0201
Peptide	GQT	TVV	PYY	PRS	PPW
Protein	EBNA2	BHRF1	BHRF1	EBNA2	EBNA1
Cycle	Latent	Lytic	Lytic	Latent	Latent
ELISPOT	220	193	225	273	203
III-2	DRB1 0401			DRB1 0701	DQB1 0201
Peptide	GQT	TVV	PYY	PRS	PPW
Protein	EBNA2	BHRF1	BHRF1	EBNA2	EBNA1
Cycle	Latent	Lytic	Lytic	Latent	Latent
ELISPOT	150	120	148	250	170
III-6	DRB1 0701	DQB1 0201
Peptide	PRS	PPW
Protein	EBNA2	EBNA1
Cycle	Latent	Latent
ELISPOT	80	55

ELISPOT = number of spots per 10⁶ peripheral blood mononuclear cells (PBMCs); MHC = major histocompatibility complex.