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. Author manuscript; available in PMC: 2014 Nov 20.
Published in final edited form as: Clin Cancer Res. 2009 Dec 15;15(24):7562–7570. doi: 10.1158/1078-0432.CCR-09-1694

Figure 2.

Figure 2

Box plots for the relative mRNA expression of CYP1B1 and GSTP1 in microdissected alveolar cells (AC) associated with the plasma nicotine and cotinine levels. The Mann-Whitney test was used for testing the differences in median gene expression across the categories of the plasma nicotine and cotinine levels. The vertical axis is log10, such that a range from 0 – 4 relative units represents a 10,000-fold range. Figure 2C, D, and G, H resolve the tobacco exposure further, depicting the significant variance in expression in CYP1B1 and GSTP1, respectively, in finer categories of plasma nicotine and cotinine.