Table 3.
Spearman’s correlation coefficients adjusted by plasma nicotine and cotinine levels, pack-years, occupational risk and family history of lung cancer, for the association between alveolar compartment and bronchial epithelial compartment in mRNA expression of CYP1B1, GSTP1 and p16
Gene expression in AC § |
Gene expression in BEC |
||||||
---|---|---|---|---|---|---|---|
CYP1B1 | GSTP1 | P16 | CYP1B1 | GSTP1 | P16 | ||
Gene expression in AC |
CYP1B1 | — | |||||
GSTP1 | 0.257 | — | |||||
P16 | 0.252 | 0.322 | — | ||||
Gene expression in BEC |
CYP1B1 | 0.679‡ | 0.124 | 0.115 | — | ||
GSTP1 | 0.030 | 0.364* | 0.075 | 0.225 | — | ||
P16 | 0.120 | −0.018 | 0.380* | 0.299 | 0.274 | — |
Definition of abbreviations: AC = Alveolar Cells; BEC = Bronchial Epithelial cells.
P < 0.001
P < 0.05.