Figure 3. Intracellular fluctuations in 2D vs. 3D.
a,b) 1D mitochondria MSDs in the two orthogonal directions with maximum ratio in displacement fluctuations for cells in (a) 2D and (b) 3D. Larger slopes (more fluid-like behavior) and magnitudes are exhibited by cells in 2D at longer time intervals. c,d) Logarithmic time derivative β of MSDs for cells in (c) 2D and (d) 3D in the corresponding 1D directions. Cells in 3D have lower β's, indicating more solid-like behavior. Error bars are s.e.m. The color code of the curves is the same as in Figure 2b.