Figure 5. Reduced response of ac1 sensilla to ammonia in Amt.

(A) Extracellular recordings of neuronal responses to a 500 ms pulse of either water or ammonia from ac1 sensilla of control and Amt¹. ac1 sensilla were identified by their location and response characteristics (see Materials and Methods). Ammonia responses were quantified by subtracting the spike frequency elicited by water (solvent) from that elicited by ammonia and are plotted in (B). (C) The spontaneous spiking activity in ac1 sensilla was significantly lower in Amt¹ mutant sensilla compared to controls (n = 9 each, p<0.0001).