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. 2014 Nov 20;8(11):e3295. doi: 10.1371/journal.pntd.0003295

Figure 1. Wild type yellow fever virus (YFV-DakH1279) is highly virulent in rhesus macaques.

Figure 1

Twenty adult female rhesus macaque (8–16 years) were infected subcutaneously with YFV-DakH1279 strain with doses ranging from 25 to 5×104 infectious units. (A) Viral loads were determined using quantitative RT-PCR and are expressed as genome copy number/ml serum. Filled circles denote animals that required humane euthanasia and open circles denote animals that survived YFV infection. (B) Kaplan-Meier survival curves following YFV-DakH1279 infection.