Table 2. Over-expressed transcripts in Group 3 and Group 4 medulloblastoma.
| Over-expressed candidate genes | Tumor suppressor candidate genes | |||||
| Probe ID | gene | fch | Probe ID | description | fch | |
| Group 3 versus NFGM | 206163_at | mab-21-like 1 (MAB21L1) | 76.7 | 207147_at | distal-less homeobox 2 (DLX2) | −62.0 |
| 205445_at | prolactin (PRL) | 45.1 | 209988_s_at | achaete-scute complex homolog 1 (ASCL1) | −32.0 | |
| 202310_s_at | collagen, type I, alpha 1 (COL1A1) | 43.9 | 213707_s_at | distal-less homeobox 5 (DLX5) | −31.8 | |
| 215076_s_at | collagen, type III, alpha 1 (COL3A1) | 38.9 | 213721_at | SRY -box 2 (SOX2) | −27.3 | |
| 206282_at | neurogenic differentiation 1 (NEUROD1) | 29.9 | 201215_at | plastin 3 (PLS3) | −25.6 | |
| 206456_at | GABA receptor, alpha 5 (GABRA5) | 26.4 | 205501_at | phosphodiesterase 10A (PDE10A) | −25.5 | |
| 204684_at | neuronal pentraxin I (NPTX1) | 18.6 | 205030_at | fatty acid binding protein 7, brain (FABP7) | −17.8 | |
| 206596_s_at | neural retina leucine zipper (NRL) | 17.9 | 205330_at | meningioma 1 (MN1) | −15.6 | |
| 202431_s_at | v-myc myelocytomatosis viral oncogene homolog (MYC) | 12.2 | 205350_at | cellular retinoic acid binding protein 1 (CRABP1) | −13.6 | |
| 206047_at | guanine nucleotide binding protein 3 (GNB3) | 12.0 | 203889_at | secretogranin V (SCG5) | −13.1 | |
| Group 4 versus NFB | 206163_at | mab-21-like 1 (MAB21L1) | 168.4 | 221805_at | neurofilament, light polypeptide (NEFL) | −55.1 |
| 205445_at | prolactin (PRL) | 21.0 | 218692_at | syntabulin (SYBU) | −40.1 | |
| 206373_at | Zic family member 1 (ZIC1) | 14.9 | 205330_at | meningioma 1 (MN1) | −35.6 | |
| 202983_at | helicase-like transcription factor (HLTF) | 11.3 | 205691_at | synaptogyrin 3 (SYNGR3) | −28.3 | |
| 221569_at | Abelson helper integration site 1 (AHI1) | 7.1 | 204081_at | neurogranin (NRGN) | −23.8 | |
| 200934_at | DEK oncogene (DEK) | 6.8 | 212148_at | pre-B-cell leukemia homeobox 1 (PBX1) | −12.4 | |
| 213029_at | nuclear factor I/B (NFIB) | 6.6 | 203548_s_at | lipoprotein lipase (LPL) | −11.8 | |
| 218515_at | GC-rich sequence DNA-binding factor 1 (GCFC1) | 6.1 | 219415_at | tweety homolog 1 (TTYH1) | −11.6 | |
| 218829_s_at | chromodomain helicase DNA binding protein 7 (CHD7) | 5.9 | 213924_at | guanine nucleotide binding protein (GNAL) | −11.1 | |
| 209337_at | PC4 and SFRS1 interacting protein 1 (PSIP1) | 5.2 | 202668_at | ephrin-B2 (EFNB2) | −10.6 | |
fch – fold change, NFGM – neural fetal germinal matrix, NFB – neural fetal brain.