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. 2014 Nov 20;9(11):e113302. doi: 10.1371/journal.pone.0113302

Table 4. Comparison of biochemical and treatment factors associated with outcome.

Factors End-point p
NO (n = 56) YES (n = 23)
Complement C3 at biopsy 1.05±0.41 1.23±0.62 0.311
Low complement C3 at biopsy (%) 14.3 17.4 0.706
Complement C4 at biopsy 0.36±0.33 0.37±0.19 0.891
Low complement C4 at biopsy (%) - - -
Serum cholesterol (mmol/L) 6.1±1.4 7.9±3.2 0.079
Serum albumin at biopsy (g/L) 26.1±6.9 25.2±8.2 0.667
Serum creatinine at biopsy (µmol/L) 124.7±86.9 315.2±229.0 0.001
Estimated MDRD GFR at biopsy (ml/min) 75.3±30.6 40.5±34.0 <0.0001
Proteinuria at biopsy (g/day) 8.1±6.9 8.3±5.2 0.872
Treatment with ACE-i/ARB (%) 92.9 87.0 0.409
Treatment with prednisone (%) 25.0 52.2 0.034
Treatment with cyclophosphamide (%) 8.9 26.1 0.071
Treatment with Azathioprine (%) 3.6 8.7 0.635

MDRD – Modification of Diet in Renal Disease; GFR – Glomerular filtration rate; ACE-I – Angiotensin converting enzyme inhibitors; ARB – Angiotensin receptor blockers.