Skip to main content
. 2014 Nov 20;9(11):e113304. doi: 10.1371/journal.pone.0113304

Figure 5. Intermittent hypoxia increased the MCP-1-enhanced adhesion of monocytes to vascular endothelial cells.

Figure 5

THP-1 cells pretreated with normoxia or intermittent hypoxia were activated by 20 ng/ml MCP-1 for another 24 hours, and then processed for cell adhesion assay. (A) Representative photos for THP-1 cells after cell adhesion assay. Adhered cells were indicated by black arrow. (Normoxia: without any treatment, Normoxia + MCP-1: with MCP-1 stimulation only, Intermittent hypoxia: with intermittent hypoxia pretreatment only, Intermittent hypoxia + MCP-1: with intermittent hypoxia pretreatment and MCP-1 stimulation) (B) Statistical results from three independent experiments were shown. Data were means and standard errors. (mean ± SE, *: P<0.05 vs. Normoxia, †: P<0.05 vs. Normoxia + MCP-1, ‡: P<0.05 vs Intermittent hypoxia).