Table 2. Univariate and multivariate analyses of overall survival of gastric adenocarcinoma patients.

Variables	n a	Univariate analyses			Multivariate analyses
		HR	(95% CI)	P value	HR	(95% CI)	P value
Age (years)				0.332
<55	230	1.000
≧55	281	1.139	0.875–1.483
Gender				0.719
Female	175	1.000
Male	338	0.951	0.723–1.251
Tumor size				<0.001*			0.690
<3 cm	84	1.000			1.000
≧3 cm	429	4.257	2.321–7.810		1.144	0.591–2.213
Tumor infiltration				<0.001*			0.167
T1	67	1.000			1.000
T2	53	7.847E3	0.000–8.853E29		1.075E4	0.000–4.118E37
T3	175	3.322E4	0.000–3.734E30		1.416E4	0.000–5.437E37
T4a	179	3.914E4	0.000–4.400E30		1.299E4	0.000–4.987E37
T4b	39	7.998E4	0.000–8.997E30		2.229E4	0.000–8.566E37
Local lymph node metastasis				<0.001*			0.011*
N0	189	1.000			1.000
N1	119	2.477	1.608–3.817		1.644	1.020–2.651
N2	82	4.022	2.605–6.209		1.915	1.118–3.281
N3	123	5.931	3.996–8.803		2.416	1.435–4.068
Distant metastasis				<0.001*			0.600
M0	466	1.000			1.000
M1	47	6.330	4.479–8.946		0.673	0.153–2.957
TNM staging				<0.001*			0.038*
1	95	1.000			1.000
2	192	10.615	3.329–33.849		2.414	0.552–10.551
3	177	26.111	8.293–82.210		3.211	0.673–15.306
4	49	91.390	28.270–295.440		18.176	2.174–151.950
PTPRD				<0.001*			0.002*
Low	261	1.000			1.000
High	252	0.474	0.357–0.630		0.629	0.469–0.845

HR, hazard ratio; CI, confidence interval; ^a Numbers of cases in each group; * Statistically significant (P<0.05).