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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Oct 9;34(12):2609–2616. doi: 10.1161/ATVBAHA.114.304587

Figure 2. Down-regulation of MMP2, MMP9, and CTSS in the aortas of ApoE−/−Opg−/− mice assessed after seven days AngII infusion.

Figure 2

A. Decreased aortic MMP2 and MMP9 in ApoE−/−Opg−/− mice (white; n=6) compared to ApoE−/−Opg+/+controls (grey; n=6) determined by zymographic analysis. Data expressed as median and interquartile range with maximum and minimum data points (whiskers) for relative density units (RDU) per μg protein (P values calculated by Mann-Whitney U test). B. Reduced CTSS in aortas from ApoE−/−Opg−/− mice (n=8) compared to ApoE−/−Opg+/+controls (n=8) determined by TaqMan® Protein Assay. Data expressed as median and interquartile range with maximum and minimum data points (whiskers) for expression relative to aortic β-actin protein; *P=0.002 (P values calculated by Mann-Whitney U test).