Table 4.
Cox regression analyses of Hepatobiliary Module (symptoms and side effects) of the FACT-Hepatobiliary and survival after adjusting for demographic, disease-, and treatment-related predictors
| Variable | B | p-value | Hazard Ratio |
95% Confidence Interval |
|
|---|---|---|---|---|---|
| Lower | Upper | ||||
| AGE | |||||
| Ref: <50 years | .037 | .925 | 1.038 | .479 | 2.249 |
| GENDER | |||||
| Ref: male | .406 | .177 | 1.501 | .833 | 2.706 |
| MELD | .006 | .849 | 1.006 | .949 | 1.066 |
| TUMOR SIZE | |||||
| Ref: <5cm | .481 | .043 | 1.617 | 1.016 | 2.574 |
| LESION NUMBER | |||||
| Ref: <2 | −.786 | .001 | .456 | .289 | .719 |
| VASCULARITY | |||||
| Ref: hypervascular | .248 | ||||
| Mixed vascularity | −.854 | .120 | .426 | .145 | 1.251 |
| Hypovascular | −.966 | .099 | .381 | .121 | 1.201 |
| VASCULAR INVASION | .815 | .001 | 2.259 | 1.402 | 3.641 |
| TREATMENT | |||||
| Ref: TACE | .244 | ||||
| 90 Yttrium | .655 | .189 | 1.924 | .725 | 5.107 |
| No treatment | .240 | .659 | 1.271 | .439 | 3.679 |
| Radiofrequency Ablation | 1.661 | .160 | 5.265 | .518 | 53.492 |
| Resection | .145 | .857 | 1.156 | .238 | 5.622 |
| HepCS | |||||
| Ref: lowest tertile | .043 | ||||
| Middle tertile | .686 | .028 | 1.986 | 1.075 | 3.668 |
| Highest tertile | .678 | .025 | 1.970 | 1.088 | 3.568 |