Table 1.
ID Numbera | Weeks post Infection |
Plasma SIV RNA (log10 copies/mL) |
CD4+ T cell count (cells/mm3) |
Route of infectionb |
MHC class I alleles |
|
---|---|---|---|---|---|---|
Acute | 2H2 | 2 | 10.35 | 822 | IV | c |
0H7 | 2 | 10.39 | 1436 | IV | c | |
8G5 | 2 | 10.52 | 1063 | IV | c | |
r03094 | 2 | 6.61 | 394 | R | c | |
4440 | 2 | 7.60 | 1736 | IV | c | |
28827 | 2 | 6.86 | d | V | c | |
| ||||||
Chronic | Rh2284-N | 12 | 6.40 | 374 | R | c |
Rh2306-N | 12 | 6.15 | 291 | R | A01, A02, B01 | |
R03116-N | 23 | 3.78 | 422 | R | A01 | |
R03103-N | 16 | 5.23 | 317 | R | c | |
R03141-N | 16 | 6.00 | 324 | R | c | |
2H2 | 36 | 8.94 | 1408 | IV | c | |
8G5-N | 43 | 8.67 | 1221 | IV | c | |
Rh2123-N | 56 | 5.62 | d | IV | A01, B30 | |
R02017-N | 88 | 5.29 | d | IV | c | |
R02076-N | 16 | 6.76 | 315 | IV | c | |
R03111-N | 15 | 6.45 | 362 | R | A02 | |
Rhau10-N | 241 | 4.11 | 569 | IV | B08 | |
Rhaxl8-N | 78 | 4.97 | 334 | R | B08 | |
4440 | 20 | 5.43 | 2099 | IV | c | |
| ||||||
SAIDSe | Rhav84 | 28 | 5.52 | 45 | IV | c |
Rhav77 | 28 | 5.71 | 123 | IV | c | |
R03094 | 22 | 6.20 | 194 | R | A01 | |
0H7-N | 20 | 11.32f | 950 | IV | c | |
2H2-N | 44 | 8.08 | 92 | IV | c | |
R97009 | 26 | 8.57 | 158 | R | c | |
R98019 | 22 | 6.51 | 489 | R | c | |
R01106-N | 81 | 4.73 | 142 | R | B08 | |
Rhaj10 | 26 | 5.46 | 53g | R | c |
Numbers that are followed by the letter āNā indicate animals who were euthanized and from which lymph nodes, spleen and GALT were obtained at necropsy.
Abbreviations for route of SIV infection: IV, intravenous, R, intra-rectal, V, intravaginal.
In situ tetramer staining not performed on this animal on this date.
Test not done.
Simian AIDS (SAIDS) was defined as an animal that had <200 CD4+ T cells/mm3 and/or a SAIDS defining illness.
Viral load was performed one week prior to this time point.
CD4+ T cell count was performed 3 months prior to this time point.