Skip to main content
. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Arthritis Rheumatol. 2014 Jul;66(7):1864–1871. doi: 10.1002/art.38630

Figure 1.

Figure 1

C protein-induced myositis (CIM) in wild type (WT) mice, L-selectin-deficient (L-selectin-/-) mice, ICAM-1-deficient (ICAM-1-/-) mice, and both L-selectin- and ICAM-1-deficient (L-selectin-/-ICAM-1-/-) mice. Mice were sacrificed at day 14 after immunization with C protein and muscle tissues were harvested. A, Representative images of muscle inflammation with hematoxylin and eosin (HE) staining. B-C, Histological score and the area of muscle fiber necrosis in each mouse group. Bars show the mean ± SEM. These results represent those obtained with 8-10 mice of each genotype. **p < 0.01. A, Original magnification: ×100 (upper panels); ×400 (lower panels).