Figure 3.
Adoptive transfer of T cells from wild type mice into L-selectin-/- mice. Mice were sacrificed at day 14 after immunization with C protein and muscle tissues were harvested. A, Representative muscle sections stained with hematoxylin and eosin (HE) and immunohistochemical images showing CD4 and CD8 staining from L-selectin-/- mice, L-selectin-/- mice with vehicle, and L-selectin-/- mice transferred with wild type T cells. B, Histological score in each mouse group. C, Numbers of CD4+ and CD8+ T cells. A, Original magnification: ×400 (upper, middle and lower panels). B-C, Bars show the mean ± SEM. These results represent those obtained with 5 mice of each group. **p < 0.01.