Table 1.
Age and sex-specific annual prevalence (per 100 population) of prescriptions for antidepressant drugs in Olmsted County, MN from 2005 to 2011
| Age and sex stratum | Annual prevalence (per 100 population)*
|
Change from 2005 to 2011 | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2005
|
2006
|
2007
|
2008
|
2009
|
2010
|
2011
|
|||||||||||
| No | Prev. | No | Prev. | No | Prev. | No | Prev. | No | Prev. | No | Prev. | No | Prev. | Prev.† | %╪ | P value§ | |
| Men (or boys) | |||||||||||||||||
| 0–4 | 0 | --- | 0 | --- | 0 | --- | 2 | --- | 1 | --- | 3 | --- | 4 | --- | --- | --- | |
| 5–12 | 90 | 1.2 | 78 | 1.0 | 84 | 1.1 | 101 | 1.3 | 108 | 1.3 | 106 | 1.3 | 100 | 1.2 | 0 | 0 | |
| 13–18 | 269 | 4.3 | 255 | 4.1 | 235 | 3.8 | 274 | 4.6 | 293 | 5.1 | 293 | 5.2 | 302 | 5.5 | 1.2 | 27.9 | |
| 19–29 | 576 | 5.2 | 688 | 6.1 | 701 | 6.3 | 745 | 6.6 | 847 | 7.6 | 852 | 7.6 | 885 | 7.9 | 2.7 | 51.9 | |
| 30–49 | 1,773 | 9.0 | 1,893 | 9.6 | 1,844 | 9.4 | 1,916 | 10.0 | 2,122 | 11.2 | 2,299 | 12.2 | 2,292 | 12.3 | 3.3 | 36.7 | |
| 50–64 | 1,158 | 11.3 | 1,251 | 11.6 | 1,255 | 11.1 | 1,379 | 11.9 | 1,700 | 14.2 | 1,864 | 15.0 | 1,977 | 15.4 | 4.1 | 36.2 | |
| 65 + | 685 | 10.4 | 739 | 10.8 | 781 | 11.0 | 935 | 12.7 | 1,100 | 14.5 | 1,294 | 16.4 | 1,363 | 16.7 | 6.3 | 60.6 | |
| Total, crude | 4,551 | 6.8 | 4,904 | 7.2 | 4,900 | 7.1 | 5,352 | 7.7 | 6,171 | 8.9 | 6,711 | 9.5 | 6,923 | 9.8 | 3.0 | 44.1 | |
| Total, standardized || | --- | 7.0 | --- | 7.4 | --- | 7.3 | --- | 7.9 | --- | 9.1 | --- | 9.7 | --- | 9.9 | 2.9 | 41.4 | 0.03 |
| Women (or girls) | |||||||||||||||||
| 0–4 | 2 | --- | 2 | --- | 2 | --- | 1 | --- | 0 | --- | 2 | --- | 1 | --- | --- | --- | |
| 5–12 | 69 | 0.9 | 60 | 0.8 | 74 | 1.0 | 89 | 1.2 | 69 | 0.9 | 69 | 0.9 | 67 | 0.8 | −0.1 | −11.1 | |
| 13–18 | 448 | 7.4 | 440 | 7.4 | 445 | 7.6 | 471 | 8.2 | 494 | 8.8 | 496 | 9.0 | 523 | 9.6 | 2.2 | 29.7 | |
| 19–29 | 1,703 | 12.9 | 1,841 | 13.6 | 1,835 | 13.3 | 1,987 | 14.1 | 2,125 | 15.4 | 2,163 | 15.2 | 2,178 | 15.1 | 2.2 | 17.1 | |
| 30–49 | 4,121 | 19.6 | 4,279 | 20.2 | 4,319 | 20.6 | 4,465 | 21.7 | 4,694 | 23.0 | 4,933 | 24.4 | 4,889 | 24.4 | 4.8 | 24.5 | |
| 50–64 | 2,741 | 24.1 | 2,897 | 24.2 | 2,990 | 23.8 | 3,287 | 25.3 | 3,783 | 28.1 | 4,152 | 29.6 | 4,337 | 29.8 | 5.7 | 23.7 | |
| 65 + | 1,587 | 17.7 | 1,727 | 18.8 | 1,793 | 19.0 | 1,998 | 20.7 | 2,423 | 24.6 | 2,748 | 27.2 | 2,911 | 28.2 | 10.5 | 59.3 | |
| Total, crude | 10,671 | 14.5 | 11,246 | 15.0 | 11,458 | 15.1 | 12,298 | 16.1 | 13,588 | 17.7 | 14,563 | 18.7 | 14,906 | 19.0 | 4.5 | 31.0 | |
| Total, standardized || | --- | 14.4 | --- | 14.9 | --- | 14.9 | --- | 15.9 | --- | 17.4 | --- | 18.4 | --- | 18.6 | 4.2 | 29.2 | 0.01 |
| Both sexes | |||||||||||||||||
| 0–4 | 2 | --- | 2 | --- | 2 | --- | 3 | --- | 1 | --- | 5 | --- | 5 | --- | --- | --- | |
| 5–12 | 159 | 1.1 | 138 | 0.9 | 158 | 1.0 | 190 | 1.2 | 177 | 1.1 | 175 | 1.1 | 167 | 1.0 | −0.1 | −9.1 | |
| 13–18 | 717 | 5.8 | 695 | 5.7 | 680 | 5.7 | 745 | 6.4 | 787 | 6.9 | 789 | 7.0 | 825 | 7.5 | 1.7 | 29.3 | |
| 19–29 | 2,279 | 9.4 | 2,529 | 10.2 | 2,536 | 10.1 | 2,732 | 10.8 | 2,972 | 11.9 | 3,015 | 11.8 | 3,063 | 11.9 | 2.5 | 26.6 | |
| 30–49 | 5,894 | 14.5 | 6,172 | 15.1 | 6,163 | 15.2 | 6,381 | 16.1 | 6,816 | 17.4 | 7,232 | 18.5 | 7,181 | 18.6 | 4.1 | 28.3 | |
| 50–64 | 3,899 | 18.0 | 4,148 | 18.2 | 4,245 | 17.8 | 4,666 | 19.0 | 5,483 | 21.5 | 6,016 | 22.7 | 6,314 | 23.0 | 5.0 | 27.8 | |
| 65 + | 2,272 | 14.6 | 2,466 | 15.4 | 2,574 | 15.6 | 2,933 | 17.2 | 3,523 | 20.2 | 4,042 | 22.5 | 4,274 | 23.1 | 8.5 | 58.2 | |
| Total, crude | 15,222 | 10.8 | 16,150 | 11.3 | 16,358 | 11.3 | 17,650 | 12.1 | 19,759 | 13.5 | 21,274 | 14.4 | 21,829 | 14.6 | 3.8 | 35.2 | |
| Total, standardized || | --- | 10.8 | --- | 11.2 | --- | 11.2 | --- | 12.0 | --- | 13.4 | --- | 14.2 | --- | 14.4 | 3.6 | 33.3 | 0.01¶ |
Number indicates the actual number of subjects who received at least one prescription for an antidepressant medication during the one-year period. For the age group 0–4 years, we did not compute the prevalence because the numbers of subjects with AD prescriptions were small (≤ 5).
Absolute change = prevalence (per 100) in 2011 minus prevalence in 2005.
Relative change = absolute change divided by the prevalence in 2005 and expressed as a percent.
P value for linear trend of increasing prevalence of prescriptions by calendar year. All models also included a quadratic term for calendar year (the quadratic term was only significant in the model with both sexes, p=0.03).
The total prevalence in men and women separately was standardized by age, and the total prevalence for both sexes combined was standardized by age and sex using the 2000 US Census population (direct standardization using the seven age groups listed in this table). These standardizations allow comparison of the total prevalence across calendar years by removing age and sex trends. However, they should not be used as national projections.
The interaction of sex by calendar year was significant indicating a higher relative increase in men compared with women (p=0.0003).