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. 2014 Nov 15;15(1):970. doi: 10.1186/1471-2164-15-970

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© Doroghazi and Buckley; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Beta-lactam and beta-lactamase inhibitor biosynthetic gene clusters. (A) The MM 4550 beta-lactamase inhibitor gene cluster from S. argenteolus is highly similar to a gene cluster found in S. pratensis IAF-45-CD (genes Sfla_0144-Sfla_0168). (B) The clavulanic acid gene cluster from S. clavuligerus (SCLAV_4187-SCLAV_4200) is highly similar to a gene cluster found in S. pratensis (genes Sfla_0550-Sfla_0565). Homologous genes are shown in the same color and genes outside of the similar regions are shown in black.