Table 2.

GO term enrichment in genes unique to IAF-45-CD

GO ID	Term	All	Unique	Expected	p-value
GO:0006259	DNA metabolic process	92	22	2.39	8.12E-14
GO:0015074	DNA integration	11	10	0.29	7.02E-13
GO:0003676	nucleic acid binding	439	34	11.29	3.40E-07
GO:0044260	cellular macromolecule metabolic process	700	42	18.2	8.12E-07
GO:0090304	nucleic acid metabolic process	555	37	14.43	1.09E-06
GO:0003677	DNA binding	356	29	9.16	3.47E-06
GO:0034641	cellular nitrogen compound metabolic pro…	699	41	18.18	3.47E-06
GO:0006310	DNA recombination	18	8	0.47	4.47E-06
GO:0006139	nucleobase-containing compound metabolic…	631	38	16.41	1.09E-05
GO:0006807	nitrogen compound metabolic process	725	41	18.85	1.19E-05
GO:0043170	macromolecule metabolic process	803	42	20.88	7.57E-05
GO:0006304	DNA modification	7	5	0.18	1.92E-04
GO:0004803	transposase activity	4	4	0.1	3.03E-04
GO:0006305	DNA alkylation	4	4	0.1	3.83E-04
GO:0006306	DNA methylation	4	4	0.1	3.83E-04
GO:0006313	transposition, DNA-mediated	4	4	0.1	3.83E-04
GO:0032196	transposition	4	4	0.1	3.83E-04
GO:0040029	regulation of gene expression, epigeneti…	4	4	0.1	3.83E-04
GO:0044237	cellular metabolic process	1096	48	28.5	1.09E-03
GO:0008152	metabolic process	2048	66	53.26	8.94E-03
GO:0043414	macromolecule methylation	7	4	0.18	1.28E-02
GO:0043412	macromolecule modification	63	9	1.64	2.28E-02
GO:0032259	methylation	16	5	0.42	3.28E-02

Gene ontology (GO) classifications were used to determine whether certain functional categories are enriched in the pool of genes unique to IAF-45-CD. The category ‘All’ indicates annotations for the entire IAF-45-CD chromosome; ‘Unique’ indicates annotations for genes unique to IAF-45-CD; ‘Expected’ indicates the number of unique genes expected if sampled at random from the pool of all unique genes found in the five genomes. The Bonferroni corrected p-values indicate the probability that the observed unique gene frequency is due to chance.